SCIENTIFIC OPINION.                              200 mg of cocoa flavanol daily

Scientific Opinion on the substantiation of a health claim related to cocoa Flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006

Following an application from B.C. Belgium n.v, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to cocoa Flavanols and maintenance of normal endothelium-dependent vasodilation.

Cocoa Flavanols are sufficiently characterised.

The claimed effect is “help maintain endothelium-dependent vasodilation which contributes to healthy blood flow” The target population proposed by the applicant is the general healthy adult population.  The Panel considers that maintenance of normal endothelium-dependent vasodilation   is a beneficial physiological effect. In weighing the evidence, the Panel took into account that cocoa Flavanols consumed for 12 weeks have been shown to increase fasting ED-FMD significantly in the target population in one human intervention study, that in another study the effect was dose-dependent and occurred after one week of consumption, that the effect was supported by two additional studies, and that it was also observed in two out of three studies in patients under pharmacological treatment for coronary artery disease, although the  mechanisms by which regular consumption of cocoa Flavanols may induce a sustained effect on fasting ED-FMD are unknown.  The Panel concludes that a cause and effect relationship has been established between the consumption of cocoa Flavanols and maintenance of normal endothelium dependent vasodilation. The following wording reflects the scientific evidence: “Cocoa Flavanols help maintain endothelium-dependent vasodilation, which contributes to normal blood flow”. In order to obtain  the claimed effect, 200 mg of cocoa  Flavanols should be consumed daily.                                   This amount could be provided by 2.5 g of high-flavanol cocoa powder or 10 g of high-flavanol dark chocolate, both  of which can be consumed in the context of a balanced diet. The target population is the general population. ©  European Food    Safety Authority (EFSA), Parma, Italy  Sept 2013


  Flavonoids content in Matcha ( young Green tea leafs) vs. red wine and apple
   According to the Department of Agriculture of the US (USDA), the mean  flavonoid            Catechins content in a 150 ml cup of green tea prepared from tea leaves or teabags  is 200.01 mg, while it is 41.7 mg in the same volume of red wine and 21.75 mg in an apple with skin that has 150 g edible portion, i.e. a rather large apple. That means one cup of green tea has the same flavonoid      potency of 4.79 glasses of red wine or 9.2 apples.


     Another ingredient consisting in a Flavanoplus blend that support well-being isthe whole Cranberry that includes the skin wich is the part of the fruit rich in flavanols and pac's.                          orproanthocyanidins and also in citricmmalic and quinic acids.           THEY CONTAIN FLAVANOIDS,ANTHOCYANINS, ELLAGIC ACID & VITAMINS C                                                                                                                                By studying the natural world and tapping into the naturally beneficial properties found in fruits and Cocoa, Flavanoplus  works  to carefully select the best fruits with specific functional benefits, such as  Proanthocyanidins founded in Cranberry a powefull anti oxidants.By adding nutritional value, we expertly craft products that enhance well-being.

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